Abstract 21545: Long-Term Outcome After Unprotected Left Main Stenting: 5-Year Follow-up of Patients From the French Left Main TAXUS Registry
Background: Few data are available on the long term outcome after PCI in patients with unprotected left main disease although this technique is being increasingly performed in our practice. The objective of our study was to assess real-world long term outcome of this strategy with Paclitaxel-eluting stent.
Methods: We performed clinical 5-year follow-up of the 291 consecutive patients treated in 4 French centers for unprotected left main stenosis from March 2003 to June 2005 and included in the French Taxus Left Main Registry.
Results: At the time of submission we have completed the clinical follow-up in 218 patients (75%) and we will obtain the remaining data for the meeting. Patients were 69 ± 11 years old, 29% were diabetic and 25% had 3-vessel disease. Euroscore was 4.8 ± 3.4 and the distal left main was involved in 78% of cases. At 5-year follow-up, the total mortality rate was 17.65% (vs 9.34 at 2 years) and cardiac 10.03% (vs 5.16% at 2 years). Q wave and non Q wave MI occurred in 0.69 and 3.81% of cases respectively (vs 0.35 and 3.46% at 2 years FU), stroke in 1.38% (vs 0.35% at 2 years) and 3.11% of patients underwent CABG (vs 2.42% at 2 years). The TLR rate was 9.0% (vs 8.30 at 2 years) and the incidence of definite and probable LM stent thrombosis was 1.04% (vs 0.69% at 2 years).
Conclusions: PCI in unprotected left main lesion with implantation of PES provides good long term outcome, even in this relatively high risk population. Cardiac mortality rate increases by 1.62% per year and all cause mortality by 2.27% per year.
- © 2010 by American Heart Association, Inc.