Abstract 21452: Association between Body Mass Index and Cardiovascular Risk Stratification in the Elderly African-American female populaion
Objective: We aimed to estimate the association of Body Mass Index (BMI) and risk of hypertension in African-American females of age 65 years or above.
Methods: This is a retrospective, cross-sectional study including African-American females of age 65 years or greater at the Obesity Research Center of St. Luke's Roosevelt Hospital, New York. Medical charts were randomly reviewed after obtaining IRB approval and data collection was conducted for height, weight, BMI, age, ethnicity, gender and hypertension. After screening based on ethnicity i.e. African American Female Population, 965 patients were isolated out of which, 631 were found to have hypertension (defined as diagnosed hypertension and use of antihypertensive medications) and 334 were without hypertension. A multivariable logistic regression was performed using a history of hypertension as the dependent variable and BMI as the primary dependent variable..
Results: The mean BMI was significantly higher in subjects with hypertension than those without (30.3 vs.29 kg/m2; p=0.003) [table 1]. A higher proportion of subjects with hypertension had a BMI >23 kg/m2 as compared to those without hypertension (88.9% vs.83.5%; p=0.023).When the log odds of having a history of hypertension was plotted against BMI as a continuous variable, we found that the odds had an increasing trend with increasing BMI and a steep increase after a BMI of 23 kg/m2. When BMI was analyzed as a categorical variable; a BMI of 23-30 kg/m2 was found to have an odds ratio of 1.43 (95% CI 1.01-2.13;p=0.05) and a BMI of >30 kg/m2 had an odds ratio of 1.76 (95% CI 1.17-2.65; p=0.007 ) when compared to a BMI of <23 kg/m2 which remained significant in both univariate and multivariate analysis.
Conclusion: We conclude that BMI is an independent predictor of hypertension in elderly African American females. Our results indicate that the risk of hypertension steadily increases significantly at BMI values of >23kg/m2 in this ethnic group. .
- © 2010 by American Heart Association, Inc.