Abstract 21446: Safety of Cardiopulmonary Exercise Testing in a High-Risk Population
Introduction: Prior studies have demonstrated the safety of standard exercise treadmill testing. The majority of the patients in these studies were low risk, including many asymptomatic patients. The purpose of this study was to examine the safety of cardiopulmonary exercise testing in a high-risk population.
Methods: All patients undergoing cardiopulmonary exercise testing are prospectively entered into a computer database which records information on demographics, symptoms, underlying cardiovascular disease, coronary artery disease, risk factors, cardiopulmonary exercise test data, and test complications. All patients with known cardiovascular disease who underwent cardiopulmonary exercise testing with measurement of peak VO2 between November 2007 and March 2010 were examined in this study. We chose to examine patients referred for assessment of peak VO2 because this population tends to have more heterogeneous and severe underlying cardiovascular disease.
Results: The final study group consisted of 5060 patients (age 57.0 ± 15.9 years, 65% male). Underlying cardiovascular diagnoses included coronary artery disease with ischemic LV dysfunction in 35.3%, idiopathic dilated cardiomyopathy in 19.5%, heart failure in 15.2%, congenital heart disease in 13.6%, hypertrophic obstructive cardiomyopathy in 11.8%, cardiac transplantation in 7.3%, pulmonary hypertension in 3.8%, amyloid heart disease in 1.5%, and cardiac sarcoid in 0.4%. Mean peak VO2 was 19.3 ± 7.0 mL/kg/min; 1192 (24%) patients had peak VO2 less than 14 mL/kg/min. There were only 8 complications.
Conclusions: Cardiopulmonary exercise testing is generally safe, even in high-risk patients. In this study the complication rate was only 0.16%. There were no fatal complications.
- © 2010 by American Heart Association, Inc.