Abstract 20980: Similar High Rates of Newly Diagnosed Abnormal Glucose Metabolism in STEMI and NSTEMI in Clinical Practice: Results of the German SWEETHEART Registry
Background: Many patients with coronary artery disease suffer from diabetes or its pre-states. Joint guidelines by the ESC and the EASD recommend testing for diabetes using OGTT in patients with established CAD and without previously known diabetes.
Methods: Since 2007, 2,749 consecutive patients with STEMI or NSTEMI were enrolled into the MI-registry SWEETHEART to identify abnormal glucose metabolism and to document acute treatment and outcome. In patients with previously unknown diabetes, oral glucose tolerance test (OGTT) was performed at day 4 after acute MI. We examined the prevalence of abnormal glucose metabolism in STEMI and NSTEMI.
Results: Patients presenting with NSTEMI were older, more often already had prior myocardial infarction and stroke and more often underwent prior PCI and CABG procedures. Patients with NSTEMI had a higher rate of known diabetes at the time of infarction. In NSTEMI, OGTT identified another 16.9% with manifest diabetes and 21.5% of patients with impaired glucose tolerance (IGT). These rates were similar in patients with STEMI.
Conclusions: Although the prevalence of known diabetes was already much higher in NSTEMI-patients, the rate of newly diagnosed diabetes or IGT was similar to that in STEMI-patients. Testing for impaired glucose metabolism using OGTT in clinical practice is as valuable in NSTEMI as in STEMI patients.
- © 2010 by American Heart Association, Inc.