Abstract 20964: Lower Rate of Major Bleeding Complications With Radial Arterial Access for Elective PCI in Clinical Practice in Europe: Results of the Euro Heart Survey PCI-Registry
Background: Over the past years the rate of radial arterial access for elective PCI has increased across Europe. However, little is known about differences in bleeding complications between radial and femoral arterial access in clinical practice.
Methods: Between 2005 and 2008, 47,407 consecutive patients undergoing PCI were enrolled into the PCI-Registry of the Euro Heart Survey Programme to document patient characteristics, PCI details and hospital complications in different PCI indications. We examined the impact of the radial versus femoral arterial access on major bleeding complications in elective PCI.
Results: A total of 22,917 patients underwent elective PCI, in 4,342 (18.5%) radial and in 18,674 (81.5%) patients femoral arterial access was chosen. Patients with radial access less often had already undergone prior CABG. During the intervention, in patients with radial arterial access low molecular weight heparin (LMWH) and GP IIb/IIIa receptor blockers were administered significantly more often. Overall, major bleeding complications were rare in both groups. In the radial access group less major bleeding complications were observed as compared to the femoral access. After correction for differences in the baseline characteristics and in antithrombotic treatment, the radial access for elective PCI was associated with a significant reduction in the risk for major bleeding complications as compared to the femoral access in clinical practice (OR 0.39, 95% CI 0.17-0.85). No difference was found in death / MI / stroke (OR 0.50, 95% CI 0.20-1.25).
- © 2010 by American Heart Association, Inc.