Abstract 20165: Laparoscopic Gastric Bypass Surgery and Adjustable Gastric Banding Significantly Improves Cardiometabolic Disease Risk Among Morbidly Obese Hispanic Adults
Background: Morbid obesity, which continues to increase in the United States, is associated with serious health and social consequences, high medical costs and disproportionally affects ethnic minorities. Very little information is available on the long-term weight- and chronic disease risk reduction effectiveness of bariatric surgery among Hispanics, however.
Hypothesis: We hypothesized that morbidly obese Hispanic adults who underwent bariatric surgery would show significant improvements in weight and cardiometabolic disease risk factors one year post-surgery.
Methods: A retrospective medical chart analysis of 751 Hispanic adults (75% female, mean age at surgery 41.5 years, SD 12.4 years) residing predominantly from Central and South America and the Caribbean who met NIH criteria (body mass index [BMI] > 35 and ≥ 1 existing comorbidity) for, and underwent gastric bypass/ banding surgery in South Florida between 2002-2009 was conducted. Pre- and one year post surgery comparative means analysis of weight and cardiometabolic disease risk factors (systolic [SBP] and diastolic blood pressure [DBP], plasma glucose, glycated hemoglobin [HbA1c], HDL, LDL, total cholesterol, and triglyceride) was conducted.
Results: Mean BMI significantly decreased from 46.12 pre-surgery to 36.58 post surgery (P<0.0001). Similarly, weight significantly decreased from pre-to post surgery (125.45 to 95.21 kilograms, respectively, P<0.0001). All cardiometabolic disease risk factors significantly improved during the same time period as well; SBP decreased from 134.74 to 120.60 mmHG, DBP decreased from 85.22 to 76.68 mmHG, plasma glucose decreased from 101.03 to 88.50 mg/dL, HDL increased from 48.76 to 55.95 mg/dL, LDL cholesterol decreased from 110.05 to 85.78 mg/dL, total cholesterol decreased from 195.08 to 161.49 mg/dL, and triglyceride decreased from 170.21 to 93.85 mg/dL and HbA1c decreased from 6.50 to 5.57 % (P<0.0001 for all pre-post comparisons).
Conclusions: Bariatric surgery results in significant weight loss and cardiometabolic disease risk reduction among Hispanic adults one year post-surgery. Bariatric surgery has the potential to be an effective treatment option for weight loss and chronic disease risk improvements in this demographic.
- © 2010 by American Heart Association, Inc.