Abstract 20134: Frequency of Psychiatric Disorders in Persons With Stress Induced Cardiomyopathy
Background: Stress induced cardiomyopathy is thought to be induced by various stressors in at risk individuals. However, the frequency of concomitant psychiatric disorders in persons with stress induced cardiomyopathy has not been well characterized.
Methods: We identified cases of stress induced cardiomyopathy in a large community based cohort in Southern California (USA). Cases were identified from 6 community medical centers. Each case underwent coronary angiography to exclude obstructive coronary artery disease and had subsequent evaluation of left ventricular function to document normalization of function and wall motion abnormalities. The frequency of a history of depression, anxiety, and use of psychiatric medications was determined.
Results: There were 53 consecutive patients identified between 2005 and 2010. The mean age for the cohort was 65 ± 12yrs (range: 41 to 87), 96% female, 83% were white, and 15% hispanic. Stress induced cardiomyopathy was confirmed in the absence of obstructive coronary artery disease and wall motion abnormalities which were extensive involving multiple coronary artery distributions. Characteristics of the clinical presentation included: angina (93%), shortness of breath (33%), congestive heart failure (19%), syncope (6%), and cardiac arrest (6%). The frequency of prior depression was 36% and anxiety disorder was 30%. The use of any psychiatric medications prior to the index event was 40%. The peak troponin I value was greater among patients with a history of depression (median and interquartile range): 2.3 (1.3 – 2.9) vs. 1.3 (0.6 – 2.5), P=0.14.
Conclusions: The frequency of psychiatric disorders and prior use of psychiatric medications is common in patients presenting with stress induced cardiomyopathy. Details of the severity of the psychiatric illness and medications used will be presented.
- © 2010 by American Heart Association, Inc.