Abstract 19654: Atrial Fibrillation as a Predictor of Mortality and Re-admissions in Patients with Pulmonary Hypertension
Introduction: Atrial fibrillation is commonly seen in patients with pulmonary hypertension (PHTN). There is a paucity of literature comparing the outcomes in pulmonary hypertensive patients with and without atrial fibrillation (AF). The aim of this study was to compare the mortality and re-admission rates in patients with PHTN with and without AF.
Hypothesis: Mortality and re-admission rates are higher in pulmonary hypertensive patients with AF versus those without AF.
Methods: This is a retrospective study where an electronic medical record system was used to gather patient information over ten years. Patients with the latest echocardiographic reading of PASP ≥ 45 mmHg and patients discharged from the hospital or visiting the outpatient clinic with the diagnosis of PHTN with or without AF were included in the study. Mortality and re-admission rates up to five years due to exacerbations of PHTN or cardiac causes were analyzed.
Results: The number of patients with PHTN without AF was 546 and 439 in those with AF. The 1-year, 3-year and 5-year mortality rates for patients with PHTN and AF vs. those without AF were the following: 22% vs. 12.7% (p<0.0001), 46.4% vs. 31.7% (p<0.0001) and 65.2% vs. 43% (p<0.0001), respectively. The re-admission rates for 1-year, 3-years and 5-years were as follows for patients with PHTN and AF vs. no AF: 46.3% vs. 26.5% (p<0.0001), 63.5% vs. 39.9% (p<0.0001) and 73.8% vs. 44.3% (p<0.0001), respectively.
Conclusions: There are significantly higher mortality and re-admission rates in the PHTN group with AF compared to those without AF. AF is a poor prognostic factor for patients with pulmonary hypertension.
- © 2010 by American Heart Association, Inc.