Abstract 19432: Prevalence of Uncontrolled Lipid Abnormalities Among Adults Self-Reporting Receiving Treatment Advice: The National Health and Nutrition Examination Survey 2003-2006
Introduction: Despite national guidelines and greater use of LDL-C-lowering drugs, lipid abnormalities persist in treated patients, particularly low HDL-C and high TG. We assessed prevalence of abnormal lipid levels in National Health and Nutrition Examination Survey (NHANES) participants who self-reported being told by a healthcare professional to take cholesterol medicine.
Methods: From NHANES 2003-2006 interview and fasting blood serum data, adults ≥20 yr who noted a healthcare professional told them to take cholesterol medicine were categorized by their LDL-C, HDL-C, and TG values using NCEP ATP III definitions. SAS 9.1.2 was used for analyses. Taylor series expansion method was used for variance estimates.
Results: Fasting lipid values were available for a projected 199.1M US adults (n = 3807); 72% (142.5M) reported ever having their cholesterol checked, and of these, 41% (58.8M) were told they had high cholesterol. Of the latter, only 54% (32.0M) (n = 670) reported a healthcare professional told them to take cholesterol medicine. Despite being told to take medicine, 59% (18.9M) had LDL-C >100 mg/dL, 26% (8.4M) had HDL-C <40/50 mg/dL (men/women), and 46% (14.7M) had TG ≥150 mg/dL (Table). By ATP III LDL-C risk groups, 68% with CHD/CHD risk equivalent were not at LDL-C goal, along with 64% and 37% of those with ≥2 risk factors and Framingham risk 10%-20% or <10%, respectively.
Conclusions: Despite dyslipidemia management guidelines, the estimated prevalence of inadequately treated dyslipidemia remains high. Especially concerning is that in the general US populace, only one-third of those assigned to high or moderately high risk status are at their LDL-C goal despite availability of efficacious lipid-lowering drugs. Prevalence of low HDL-C and high TG, both contributors to CV risk burden, also remains high. Novel approaches (eg, simplifying guidelines, augmenting educational approaches) should be considered to further improve lipid goal attainment rates.
- © 2010 by American Heart Association, Inc.