Abstract 19422: 2D and 3D Diastolic Strain Rate by Speckle Tracking for assessing Left Ventricular End Diastolic Pressure
Purpose: The aim of the study was to compare the accuracy of longitudinal diastolic velocity and strain rate (SR) obtained by tissue Doppler imaging (TDI), 2D and 3D speckle tracking in assessing left ventricular end diastolic pressure (LVEDP)
Methods: EDLVP measurement was performed in 40 consecutive patients referred for coronary angiogram (mean age= 60 ± 15 years, mean EF= 41 ± 14). A comprehensive transthoracic echocardiography (Artida, Toshiba) study was performed immediately after LVEDP measurement. Echocardiography data acquired included mitral early diastolic velocity (E) by conventional pulsed Doppler, early diastolic mitral annulus velocity by TDI (E'), and high frame rate 2 and 3D apical views. Global longitudinal SR by 2D (2DEGSR) and 3D (3DEGSR) were assessed using longitudinal strain curves from speckle tracking analysis. LV filling pressure estimated using echocardiography data (E/E', E/2DEGSR, E/3DEGSR) were correlated to invasive LVEDP measurement.
Results: On the whole, LVEDP averaged 13mmHg (5 to 32,) and best correlated with LV filling pressure assessed by 2D speckle tracking (r2=0.65, p<0.0001). In contrast, conventional E/E' by TDI and E/3DEGSR poorly correlated with LVEDP (see Figure).
Conclusions: Longitudinal diastolic strain rate by 2D and not 3D speckle tracking appears superior to conventional E/E' by TDI for assessing LV filling pressure.
- © 2010 by American Heart Association, Inc.