Abstract 19385: The Effect of Prolonged Combined Thermal and Electrical Muscle Stimulation on Body Composition and Lipolytic Activity in Obese Subjects
Purpose: It is unclear whether prolonged electrical muscle stimulation can increase lipolytic activity and reduce body fat in obese individuals. The purpose of this study was to investigate the effect of prolonged combined thermal and electrical muscle stimulation (cTEMS) on fat mass, lean mass, visceral fat and lipolytic activity in adipose tissue.
Methods: 12 obese (BMI>30) individuals received cTEMS in three 60-minute sessions per week over 8 weeks. Activity levels and nutritional habits were kept unchanged and controlled with accelerometer and nutritional questionnaire. Before and after the stimulation period, body composition was assessed by Dual Energy X-ray absorptiometry and visceral fat area estimated by Bioelectrical Impedance Analysis. Lipolytic activity in abdominal adipose tissue was determined by 24 hour of microdialysis on a sedentary day and in addition, functional capacity was assessed by VO2peak.
Results: No significant changes in body composition were observed. The visceral fat area was unchanged. Mean microdialytic glycerol concentration over 24 hours, as index of sedentary lipolytic activity, increased from 238 ± 60 μM to 306 ± 55 μM (p<0,0001). Further, 8 weeks of cTEMS significantly raised VO2peak by 9,6% (28,95 ± 5,71 ml/kg/min to 31,74 ± 6,21 ml/kg/min; p=0,0140).
Conclusions: In obese individuals with unchanged lifestyle, 8 weeks of cTEMS significantly increased the lipolytic activity in abdominal adipose tissue and improved functional capacity. There was no change in body composition or visceral fat area during this relatively short stimulation period.
- © 2010 by American Heart Association, Inc.