Abstract 18247: High 5-Year-Mortality in Patients with Stable Angina and First Angiographic Diagnosis of Coronary Artery Disease in Clinical Practice in Germany: Results of the STAR Registry
Background: Approximately 1.6–3.2 Mio patients in Germany suffer from stable angina (AP). Little is known about the long-term outcome of patients with documented coronary artery disease (CAD) and AP in clinical practice.
Methods: Between Sept 2001 and March 2003, a total of 2,002 consecutive patients with AP and first angiographic diagnosis of CAD were enrolled in the STAR-Registry (50 centres) and followed for five years. We examined the predictors of five-year-mortality of CAD with AP in clinical practice.
Results: Patients with AP and documented CAD had a mean age of 66 years, 30.0% were female. Co-morbidities were as follows: diabetes 26.4%, prior myocardial infarction 8.2%, prior stroke 4.7%, peripheral artery disease 9.8%. Coronary angiography revealed 1-vessel-disease in 44.1%, 2-vessel-disease in 30.0%, and 3-vessel-disease in 25.9%. PCI was performed at the time of the first angiographic diagnosis of CAD in 46.0%. The rate of PCI within one year after the first angiographic diagnosis was 19.1% and 16.7% between year 1 and 5. The 5-year-rate of CABG was 28.8%. Mortality at five years after the first angiographic diagnosis of CAD was 18.5% in the overall population.
Conclusions: Increasing age, male gender, and co-morbidities like prior stroke, prior myocardial infarction and diabetes are strong predictors of an increased 5-year-mortality of stable angina in clinical practice. Interventional therapy in patients with stable angina did not impact on 5-year-mortality.
- © 2010 by American Heart Association, Inc.