Abstract 181: Comparison of Defibrillation Efficacy Between Two Pads Placements in a Pediatric Pig Model of Cardiac Arrest
Background: Placement of defibrillation pads at ideal anatomical sites constitutes an integral aspect of optimal defibrillation. However, the optimal placements of pediatric pads are still undetermined. In the current study, we compared the effects of two different pads positions on defibrillation success rate in a pediatric pig model of cardiac arrest.
Methods: Eight male pigs, 13.5±1.0 kg, were randomized to receive shocks using either anterior-anterior or anterior-posterior pads position. The ZOLL pediatric pads, pedi-padz II, were used in the study. For each animal, ventricular fibrillation (VF) was induced and untreated for 30 secs. A randomized 10, 20 30, 50 or 70 J biphasic electrical shock was then attempted. If the defibrillation failed to terminate VF, a 100 J rescuer shock was delivered. After a recovery interval of 5 mins, the sequence was repeated for a total of 30 test shocks for each animal, with 6 shocks for each of the energy settings. The dose response curves were constructed and the defibrillation thresholds were compared.
Results: The aggregated success rate for anterior-posterior placement was significantly higher as compared to anterior-anterior placement (66.7% vs. 43.3%, p<0.0005) at the same experimental settings. As shown in Figure 1, a significantly higher success rate was observed when the delivered energy was between 20 to 50 J, without significant differences in impedance, defibrillation energy and current between the two groups. When energy was increased to 70 J, the anterior-posterior positioning yielded a success rate of 100%, but only 85% on anterior-anterior group.
Conclusion: In this pediatric model of cardiac arrest, the anterior-posterior placement yielded a higher success rate compared to anterior-anterior when pediatric pads were used.
- © 2010 by American Heart Association, Inc.