Abstract 17855: Prospective Evaluation Of Quality-of-life Among Patients Undergoing Transcatheter Aortic Valve Implantation: 1-year Follow-up Results
Background: Given the paucity of data on the impact of transcatheter aortic valve implantation (TAVI) on quality of life (QoL), we examined whether TAVI is associated with an improvement in physical and/or mental health at 1-year follow-up.
Methods: From 6/2007 to 6/2010 we have performed a total of 400 valve implantations at our center. We performed a prospective analysis of 68 patients who underwent TAVI with either the Medtronic CoreValve or Edwards SAPIEN device and had completed 1-year follow-up. QoL was measured by using the Short Form 36 Health Survey questionnaire (SF-36) at baseline and 1-year follow-up. The SF-36 allows assessment of both physical and mental health components.
Results: The mean age of the patients was 79.9±6.5 years, 60% were female and the logEuroSCORE was 18.6%±10.6. A transfemoral CoreValve and transapical Edwards SAPIEN was implanted in 53 patients (78%) and 15 (22%), respectively At 1-year follow-up, there were significant improvements in the SF-36 scores for physical functioning (baseline 35.3±2.8 vs. 1-year follow-up 45.0; p<; 0.001), bodily pain (59.5±3.7 vs. 66.7±3.2; p<0.05), general health (46.6±1.8 vs. 54.6 ±2.8, p<0.01) and vitality (35.0± 2.6 vs. 47.6±2.3; p<0.001). A statistical trend was found for role-physical (22.1± 3.9 vs. 32.1±5.1; p=0.1) and mental health (62.2±2.7 vs. 66.7±2.5; p=0.1). No significant improvement could be detected for social-functioning (75.6±3.3 vs. 76.1±3.3; p=0.85) and role-emotional (67.4± 5.9 vs. 66.4± 5.8; p=0.75). At 1-year follow-up, the various physical and mental scores were comparable to an age-matched standard population.
Conclusions: In patients not eligible for conventional AVR, TAVI leads to a considerable physical health improvement at 1-year follow-up. However, there was no improvement in mental health scores.
- © 2010 by American Heart Association, Inc.