Abstract 15070: Idiopathic Atrial Fibrillation: Does Age Matter?
Purpose: An ‘age=60years’ criterion is used as cut off for the diagnosis of idiopathic atrial fibrillation (AF). We investigated the role of ageing in patients with idiopathic AF.
Methods: Out of 3,978 AF patients in the Euro Heart Survey on AF with known follow-up, 119 (3%) patients had idiopathic AF. Patients with hypertension, antihypertensive drugs, diabetes, congestive heart failure, coronary artery or peripheral vascular disease, previous stroke, thyroid, pulmonary and renal disease, or abnormal echocardiogram, were excluded. However, we disregarded enlarged atria as a structural abnormality since the atria may enlarge by AF itself.
Results: Persistent/permanent AF is more prevalent in the older idiopathic AF patients, who had a greater pulse pressure. After correction for body mass index, left atrial size did not differ in relation to age. Rhythm control is frequently applied in both age groups and led to a trend for more hospital visits in the younger group. Only 2 paroxysmal AF patients progressed to permanent AF (1 in each group). No cardiovascular events occurred during 1 year follow-up.
Conclusion:Half of idiopathic AF patients are ≥60years but their vascular profile and short term prognosis is very favorable. Idiopathic AF may be more closer related to the “biological age” of the cardiovascular system, than with someone' “calendar age”. We suggest that the use of a cutoff for age in the definition of idiopathic AF seems questionable.
- © 2010 by American Heart Association, Inc.