Abstract 145: Clinical Events Within 48-Hour After ROSC Associated With Hospital Outcome of Cardiac Arrest Patients Admitted to ICU
Introduction:The aim of this study was to determine clinical events present within 48-hour after resumption of spontaneous circulation (ROSC) that may be associated with hospital outcome of cardiac arrest patients survived to ICU admission.
Methods: We retrospectively evaluted the medical records of all post-cardiac arrest adult patients (age >=18 years) admitted to a general ICU of teaching hospital after sustained ROSC for more than 6 hours during January 1997 to December 2007. Following clinical events within 48-hour after ROSC were reviewed: unconsciousness (can not response to the verbal orders), seizures/myoclonus, hypotension (systolic blood pressure <=90mmHg), dysrhythmia, hyperthermia (axillary temperature >=38.5°C), polyuria (urine output >=4000mL/d), oliguria (urine output <=400mL/d), hyperglycemia (>=13.9mmol/L), upper gastrointestinal bleeding, low PaO2/FiO2 index (<300mmHg), infection.
Results: Sixty one males (59.8%) and 41 females (40.2%) were enrolled in this study. Mean age was 56±18 years. Thirty patients survived to hospital discharge, and 14 patients (13.7%) had good neurological outcomes (Cerebral Performance Category scale 1 or 2). Prevalence of clinical events are shown in Table 1. Unconsciousness, hypotension, hyperthermia, polyuria, hyperglycemia were significantly associated with hosptial outcome (Table 2).
Conclusions: Clinical events present within 48-hour after ROSC are associated with hospital outcome after ICU admission.
- © 2010 by American Heart Association, Inc.