Abstract 14351: Atherosclerotic Risk Factors Remain Less Intensively Treated in Patients With Peripheral Arterial Disease Than in Patients With Coronary Artery Disease
Introduction: The presence of peripheral arterial disease (PAD) is a coronary artery disease (CAD) equivalent and it is associated with an increase in cardiovascular mortality. The intensity of risk factor modification in patients with PAD alone versus those with CAD alone or both CAD+PAD has not been well studied.
Methods: We analyzed 302 patients with CAD or PAD at baseline and over a 2 year period followed at a Veterans Administration hospital. Patients were classified into three groups: PAD alone (n=84), CAD alone (n=93), and CAD+PAD (n=125). Cardiovascular risk factors and guideline recommended therapies were assessed among the 3 groups. ANOVA and Chi-square tests with post-hoc adjustment were used to compare means and proportions, respectively.
Results: At baseline, PAD patients had higher systolic blood pressure when compared to CAD or CAD+PAD patients (140.5±18.3, 125.1±19.2, 133.2±21.8 mmHg, respectively, p < 0.001) and had higher LDL levels (125.6±34.7, 103.9±30.8, 111.2±39.5 mg/dL, respectively, p=0.001). Patients with PAD were consistently less often treated with anti-hypertensive, anti-lipid, or anti-platelet medications when compared to CAD and CAD+PAD patients (Figure).
Conclusion: Patients with PAD alone are undertreated compared to patients with CAD or CAD+PAD. An opportunity exists for better adherence to risk factor modification in PAD patients based on guideline recommendations.
- © 2010 by American Heart Association, Inc.