Abstract 13365: Kidney Enhancement Following Percutaneous Coronary Intervention Predicts Long-Term Poor Clinical Outcomes
Background: Contrast-induced nephropathy is associated with poor clinical outcomes. Kidney enhancement on plain abdominal X-ray following percutaneous coronary intervention is a predictor of contrast-induced nephropathy in a short period. However, there is no information about the prognostic significance of kidney enhancement.
Methods: We retrospectively investigated 126 consecutive patients who underwent percutaneous coronary intervention and performed with abdominal X-ray within 24 hours. Kidney enhancement was defined positive when the density of the kidneys was higher than that of lumbar vertebrae. The primary end point was the incidence of renal replacement therapy or death.
Results: In 126 patients, 11 patients had kidney enhancement and 115 patients did not have kidney enhancement. There were no significant differences in age, gender, the incidence of hypertension or diabetes mellitus or anemia, time of X-ray post percutaneous coronary intervention, serum creatinine level at the entry and contrast volume administered between patients with and without kidney enhancement. During a mean follow-up period of 21.4±15.7 months, 5 of 11 patients with kidney enhancement had renal replacement therapy or death ,while the poor clinical outcome was observed in only 12 of 115 patients without kidney enhancement. Kaplan-Meyer analysis revealed that there was a significant difference of the probability of the end point between patients with and without kidney enhancement (45.5% vs 10.4%, respectively; p<0.01).
Conclusion: Kidney enhancement following percutaneous coronary intervention would predict long-term clinical poor outcomes.
- © 2010 by American Heart Association, Inc.