Abstract 12585: Gender and Left Atrial Ablation for Atrial Fibríllation: Outcome Data from the German Ablation Registry
Women tend to be underrepresented in many clinical trials and often seem to be referred to undergo invasive procedures less frequently. The German Ablation Registry (GAR) is a designed as a multi-center prospective registry for electrophysiologic ablation procedures. It provides patient- and procedural characteristics and short- and long- term outcome data from 55 ablation centers. From March 2007 until May 2010, 6066 consecutive patients undergoing left atrial ablation for atrial fibrillation (AF) were included: 1970 (32.5%) f (female), 4096, 67.5% m (male) patients. This is the first report about preliminary outcome data.
Results: DM (f: 9.4%, m: 7.8%, p<0.05), hypertension (f: 66.1%, m: 58.1%, p<0.01) and valvular heart disease (f: 9.8%, m: 8.0%, p<0.05) were more common in female patients whereas CAD (f: 13.0%, m: 21.3%, p<0.05) and cardiomyopathies (f: 2.7%, m: 5.0%, p<0.0001) were more frequent in males. Women were older (f: 66y [59–70y], m: 61y [53–68y], p<0.001) and had more paroxysmal AF (f: 67.1%, m: 58.7%, p<0.0001). Males had more persistent (f: 24.6%, m 32.2%, p<0.0001) and permanent AF (f: 6.5%, m 9.1%, p<0.001). Mean CHADS2 score was similar (f: 0.44, m: 0.43, p=0.87). The table provides immediate and 1 y outcome data. MACE: Death, MI. MACCE: Death MI, Stroke.
Conclusion: Male referrals predominated the registry. Groin complications and repeat hospitalisations were more common in women and acute strokes, (albeit small in number) also tended to be more common in female patients. Long term outcome (success and adverse events) were very similar in female as in male patients despite higher age in the female population.
- © 2010 by American Heart Association, Inc.