Abstract 12529: Peak Systolic Velocity of Pulmonary Venous Flow is Closely Associated with Left Ventricular Global Longitudinal Speckle Strain in Patients with Cardiomyopathy
Background: It is reported that global longitudinal speckle strain (GLS) is a superior predictor of outcome to either ejection fraction or wall motion score index in patients with heart diseases. On the other hand, pulmonary venous flow (PVF) peak systolic velocity (S-vel) is reported to correlate with systolic longitudinal mitral annular contraction. We hypothesized that the GLS is associated with the peak systolic PVF S-vel.
Methods: We examined consecutive 909 patients who were suspected to have heart failure symptoms. We divided patients into 3 groups; cardiomyopathy (CM) group (n=227), ischemic heart disease (IHD) group (n=571), and valvular heart (VH) disease (n=111). In addition to routine echocardiographic and Doppler flow (transmitral, and PVF velocity) assessments, the LV GLS from apical 4 chamber view and the LV global circumferential strain from short axis view of papillary muscle level were measured in each examination.
Results: Linear regression analysis demonstrated that the PVF S-vel was significantly correlated with the GLS in overall patients (R=0.455, P<0.0001). Subgroup analysis demonstrated that the PVF S-vel was strongly associated with the GLS in CM group (R=0.615, P<0.0001). Contrary to the finding, the correlation between the PVF S-vel and the GLS was poor in IHD (R=0.382), and in VH group (R=0.402).
Conclusions: There is a strong correlation between the PVF S-vel and the GLS especially in patients with CM. Simple measurement of the PVF S-vel could be an alternative predictor of outcome in patients with cardiomyopathy.
- © 2010 by American Heart Association, Inc.