Abstract 4614: Implications of Clopidogrel and Aspirin Withdrawal in Drug Eluting Stents Patients
The implication of oral anti-platelet medication withdrawal for short term after one year in DES patients is unclear.
Method: A telephone and mail survey was performed on patients with drug eluting stents placed at Mount Sinai Hospital between May 1, 2003 to May 1, 2008.
Result: Total of 9710 patients (14648 procedures) were contacted; information for 5681 patients were available. Mean duration of follow-up was 1108±446 days (367 to 2078 days). A large number of patients (16.8%) had Plavix stopped permanently after 1 year. The rate of stent thrombosis or Myocardial infarction is very low with temporary withdrawal of aspirin or Plavix, or with permanent withdrawal of Plavix after 1 year. Stopping both Aspirin and Plavix results in numerically higher rate of stent thrombosis or MI, though this is not statistically significant.
Conclusion: Temporary withdrawal of Plavix and Aspirin and permanent withdrwal of Plavix after 1 year did not result in higher stent thrombosis or MI rate. Stopping both aspirin and Plavix resulted in non-statistically significantly higher rate of stent thrombosis.