Abstract 4548: A Novel Risk Score for Percutaneous Coronary Intervention Outcome Assessment: Weighting the Importance of Anemia
Background: Clinical and angiographic risk factors associated with adverse outcomes after percutaneous coronary intervention (PCI) have been identified and included in previous validated risk scores. However, the presence of anemia before PCI and/or the development of it after PCI – factors known to increase mortality and morbidity after PCI – have not been included in any model.
Aim: To create and validate a PCI risk score that includes the hematocrit at baseline and hematocrit drop for patients undergoing PCI.
Methods: We analyzed consecutive patients who underwent PCI from 2003 to 2005. Logistic regression and bootstrap methods were used to build an integer risk score for estimating the risk of death and myocardial infarction (MI) at 30 days after PCI using clinical, angiographic and procedural characteristics. The risk score was validated in the set of patients who underwent PCI from 2006 to 2007.
Results: Among 5,264 procedures, 1 angiographic and 5 clinical variables were significantly correlated with the outcome: cardiogenic shock, history of diabetes, lower baseline hematocrit, greater hematocrit drop after PCI, type C lesion and older age. In the validation set-population (n=763), the model fitted the data adequately. The average receiver operating characteristic curve area was 0.824 (SD, 0.038). (Figure⇓)
Conclusion: Inclusion of the baseline and post-PCI hematocrit in a novel integer risk score for PCI values the significance of anemia before and after PCI to predict clinical outcome at 30 days.