Abstract 4378: More Than 10 Years Clinical Follow-up After Endovascular Therapy in Patients With Intermittent Claudication
Background: A little is known about long-term outcomes of patients with intermittent claudication (IC) undergoing endovascular therapy (EVT). In this study, we sought to investigate its impact on survival.
Methods: This is the study of 271 consecutive patients with IC that were treated by EVT. We examined long-term clinical outcomes of patients received EVT from Jan.1990 to Dec.1998.
Results: Clinical follow-up information was obtained in 251 patients (93%) at 10 years. The follow-up interval of the 142 survivors was 11.7 +/− 2.9 years (range, 1–19 years). All patients were discharged alive and constituted the study population for long-term outcomes. During the follow-up period, 132 (49%) patients died (cardiac death 48%, non-cardiac vascular death 18%). Amputation was performed in only 1 patient (0.4%). Kaplan-Meyer curve showed that freedom from target vessel revascularization (TVR) was 79% (5-year), 70% (10-year), and 67% (15-year), freedom from death was 73% (5-year), 58% (10-year), and 43% (15-year) and freedom from major adverse cardiovascular events (MACE defined as death, mypcardial infarction and stroke) was 69% (5-year), 49% (10-year), and 34% (15-year). Using multivariate Cox regression, age, coronary artery disease (CAD), diabetes, and chronic kidney disease (CKD) were independent predictors in overall survival.
Conclusions: Regardless of good clinical patency of treated legs, the survival of patients with IC was poor. Age, CAD, diabetes, and CKD were identified as independent predictors of late mortality.