Abstract 3268: What Kind of Patients Have Great Atrial Asynchrony? Utility of Non-invasive Assessment by Tissue Doppler Imaging
Background: Heart failure is often associated with atrial asynchrony. However, little is known about what plays an important role in causing atrial asynchrony.
Methods: Tissue Doppler imaging (TDI) was performed in 241 consecutive patients (122 women; 54±11 years) with normal sinus rhythm. In the apical long-axis view, the time difference from the onset of the P wave to the onset of the A wave in the right atrium (P-RA), interatrial septum (P-IAS), and left atrium (P-LA) was measured. Atrial asynchrony was defined as the difference between the P-IAS and P-RA (RA-asynchrony), P-LA and P-IAS (LA-asynchrony), and P-LA and P-RA (interatrial-asynchrony). The relationship of the Atrial asynchrony to the clinical variables was examined.
Results: The interatrial- and LA-asynchrony were both greater in patients with hypertension, left ventricular hypertrophy (LVH), and structural heart disease than in those without (See Table⇓). In patients with LVH, the RA-asynchrony was also greater than in those without (p=0.019). The age (odds ratio=1.02; p<0.05), female gender (odds ratio=2.33; p<0.05), and LVH (odds ratio=1.02; p<0.01) were associated with interatrial-asynchrony. LVH tended to be associated with LA-asynchrony (odds ratio=1.01; p=0.06).
Conclusions: The presence of LVH, SHD, and hypertension may predict great atrial-asynchrony, especially interatrial-asynchrony. TDI is useful for directly and non-invasively assessing atrial-asynchrony.