Abstract 2466: Therapeutic Hypothermia With Less Invasive Cardiopulmonary Bypass Circuit for Out-of-Hospital Cardiac Arrest
Background: Mild therapeutic hypothermia has been integrated to improve the neurological outcome of cardiac arrest with ventricular fibrillation. We introduce our rapid and safety hypothermia procedure with Less Invasive Cardiopulmonary bypass Hypothermia (LICH) for ROSC patients. The aim of this study is to evaluate new procedure on the outcome of cardiac arrest patients.
Methods: From January 2007 to May 2009, 28 patients were treated with mild hypothermia. The patients were divided into LICH procedure (Group L) and traditional cold blanket procedure (Group C). LICH procedure was indicated for unconscious ROSC patients under 75 years old after cardiogenic cardiopulmonary arrest (CPA) with witness, excluded with brain hemorrhage, traumatic CPA, and easily bleeding. LICH procedure was induced quickly via narrow child cannula with low-perfusion. Any complications, time to target temperature, stability of temperature, and neurological outcome were compared. A favorable outcome was defined as a Cerebral Performance Category (CPC) of 1–2.
Results: There was no significant characteristic differences between group L (N=14) and group C (N=14). As compared with group C, Group L had higher rates of temperature stability (p<0.01), temperature over shoot (93% vs. 0%, p<0.01), and quick induction (11min vs. 307min, p<0.01). But, the mortality (7% vs. 7%), and the rate of favorable neurological outcome (79% vs. 71%) showed no differences in both groups. Any life-threatening complications were not seen in both groups.
Conclusions: These results indicated LICH procedure was safety and fastest way to induce therapeutic hypothermia. In addition, low-perfusion child bypass circuit system had some benefit compare with adult circuit.