Abstract 2123: A Simple Echocardiographic Screening Tool for Aortic Root Dilatation in Children With Marfan Syndrome
Aim: We sought to develop a simple echocardiographic screening tool for aortic root dilation in pediatric patients with Marfan syndrome.
Introduction: Aortic root dilation is the most common cause of morbidity and mortality in Marfan syndrome. It is traditionally defined by nomograms, relating aortic root size to height or body surface area. We used the descending aorta (DAo) as an internal reference, which eliminates the need for nomograms when screening for aortic root dilation.
Methods: Diameter of aortic root at the sinus of Valsalva and DAo were retrospectively measured in 35 Marfan patients and 52 age-matched controls. All measurements were obtained from inner edge to inner edge, in systole, in a single parasternal long-axis view. Root:DAo ratio was calculated.
Results: Root:DAo ratio < 2 indicates normal size aortic root, since Root:DAo ratio ≥ 2 is 100% sensitive for root dilation. Root:DAo ratio ≥ 2.3 is 100% specific and confirms aortic root dilation.
Conclusion: Root:DAo ratio is a simple, rapid and valuable screening test for aortic root dilation, independent of nomograms and body size.