Abstract 2122: Advanced Semi-Automated Display and Volume Computation for 4D Fetal Cardiac Images
Background: The expertise required to display and measure 3D/4D fetal heart images has limited its application. We developed a unique method for thresholding, display and measurement of fetal heart images.
Methods: We studied 15 fetuses with postnatally confirmed diagnoses: 13 normal fetal hearts, 19 to 29 completed weeks’ gestation, one with d-transposition of the great arteries (d-TGA) at 23 weeks and one with hypoplastic left heart syndrome (HLHS) at 22 weeks. Volumes were acquired with the Voluson 730 Expert and E8 ultrasound systems both capable of spatiotemporal image correlation (STIC), using an RAB 4 – 8 transducer, and were analyzed off-line using a novel algorithm designed for ovarian folliculometry (SonoAVC, 4DView version 7.0). For the fetal heart, “seeds” were placed manually inside the individual cavities which were then expanded to fill hypoechoic spaces in the volume. The multiplanar display with 3 cross-sections was augmented by a 3D-rendered virtual cast.
Results: In addition to the unique display, volume calculations could be performed for the cardiac ventricles. Ejection fractions (EF) for normal right ventricles (RV) were 68 ± 4%, whereas for left ventricles (LV), it was 63 ± 6%. In the case of HLHS, during end-diastole and end-systole the RV measured 1.15ml and 0.34ml (EF 70%), but the LV was 0.12ml and 0.09ml (EF 25%).
Conclusions: This method is an important step towards semiautomated fetal volume echocardiography and quantification.