Abstract 1934: Right Ventricle Dilatation Results in Deterioration of Right Ventricle Longitudinal Systolic Velocity and Acceleration: 70 Case Analysis of Right Ventricle Systolic Deformation
Backgrounds: Right ventricle (RV) exposed to volume overload presents RV dilatation, resulting in decreased RV function. Longitudinal systolic deformation of RV is shown to reflect global preload recruitable stroke work of RV. However, impact of RV dilatation on RV longitudinal systolic deformation is poorly understood.
Objective: We hypothesized that RV dilatation results in decline of RV longitudinal systolic velocity and systolic acceleration.
Methods: Between 2006 and 2008, 70 consecutive patients (32 patients with normal heart function as a control and 38 patients with RV dilatation after correction of tetralogy of Fallot) underwent ECG gated 64-row multislice computed tomography. Length (LI) from RV apex to tricuspid valve indexed to body surface area was measured in each timephase of systolic phase. LIes was defined as LI at endsystolic timephase. Systolic velocity (V) was defined as difference of LI at 2 successive timephase divided by systolic time (T) calculated from heart rate. Systolic acceleration (A) was defined as difference of two successive V divided by T. Peak V and peak A were defined as Vmax and Amax, respectively. Each indices were correlated with RV endsystolic volume index (RVESVI).
Results: LIes correlated strongly with RVESVI (r=0.73, p<0.001). Vmax had inverse correlation with RVESVI (r=−0.39, p=0.003). Vmax and Amax correlated inversely with LIes (r=−0.68, p<0.001 and r=−0.32, p=0.011).
Conclusions: We found RV dilatation correlating strongly with elongation of LIes. Vmax and Amax had correlation with LIes, insisting elongation of RV longitudinal axis resulting in deterioration of RV longitudinal systolic velocity and acceleration.