Abstract 1778: 4-Dimensional Echocardiography Provides a Robust Method to Quantify Right Ventricular Volume and Stroke Volume: An in-vitro Validation Study
Background: Accurate quantification of right ventricular (RV) stroke volume (SV) has remained clinically challenging despite advances in cardiac imaging due to the fundamental complex structural geometry of the RV. We tested the accuracy of a newly developed Tom-Tec 4-dimensional (4D) echocardiography method for calculating SV of the RV.
Methods: Five freshly harvested pig hearts were dissected. After removal of the right atrium, the tricuspid valve was closed using a tricuspid valve like patch, and then connected at the pulmonary artery root to a pulsatile pump and placed in a water bath. Five different SVs (30 to 70 ml/beat) were studied at a pump rate of 60 bpm. Pump gated full volume image loops of the right ventricle were acquired using a Phillips iE33 system with an X-7–2 matrix array transducer at maximized frame rates. Data were analyzed offline for RV volumes using TomTec 4D RV Function.
Results: 82 loops were analyzed. Although the average computed SV of the RV was slightly smaller than the actual pump SV, with increase in actual SV, the computed SV also increased (at 30ml =27.88 ±5.77ml, 40ml =35.88±6.34ml, 50ml =46.79.88 ±9.56ml, 60ml =53.49 ±11.56ml, 70ml =60.34 ±17.56ml). Close correlation was found between the computed SV and the actual SV (r2=0.77, p<0.01).
Conclusion: The new 4D RV Function program has great potential for future clinical evaluation of RV volume.