Abstract 1394: Lifestyle Interventions for the Metabolic Syndrome Using Cardiac Rehab Resources
Background: The 5 components of the metabolic syndrome (MetSyn) are each responsive to life style change. We sought to determine the value of improving metabolic fitness (MetFit) using 12 once weekly 90 minute sessions of exercise (45m each session), nutrition, and stress management using cardiac rehab resources.
Methods: All patients (pts) were physician referred with 3 or more criteria of the MetSyn. Anthropomorphic, physiologic, and biochemical studies were obtained at baseline and 12 wks. The Patient Health Questionairre-9 (PHQ-9) was used to detect depressive (Dep) symptoms. Pts were considered drop outs if they did not attend 75% of the 12 education and exercise sessions.
Results: 95 pts enrolled MetFit between Jun’05 and Oct’08. Average age was 52.1±12.2 yrs, 64.2% were female, 81.1% married, 81.9% employed, 65.3% had a bachelors degree, and 35.8% were diabetic. 17.4% of pts had a PHQ-9 ≥10. There was no difference in baseline Dep scores by age, sex, marital or work status. The prevalence of the 5 MetSyn components was: 96.8% visceral obesity, 55.8% elevated triglycerides, 68.4% low HDL-C, 65.3% elevated BP or treated hypertension, and 71.6% elevated glucose. The results are summarized in the Table⇓. By 12 wks, 35.8% had ≤2 MetSyn criteria (p<0.0001). 51.6% of pts were considered drop outs. The Dep score at baseline did not predict drop out. There was no relationship between Dep scores or other baseline variables and outcome.
Conclusion: A lifestyle intervention program targeting the Metsyn using a cardiac rehab program is very effective for reducing metabolic and coronary risk. Depressive symptoms and other baseline variables do not preclude success.