Abstract 1391: Predictors of Physical Activity in Kidney Transplant Recipients
Coronary artery disease (CAD) is the leading cause of mortality in kidney transplant recipients. Physical activity can reduce cardiovascular risk factors. However, after transplant, few recipients engage in levels of physical activity sufficient to achieve this outcome. The aims of this study were to describe physical activity and to identify factors associated with physical activity in a cohort of kidney transplant recipients.
Methods: The Physical Activity Scale for the Elderly (PASE) questionnaire was administered to 68 kidney transplant recipients at clinic follow up visits conducted a median of 6 months (range 5–7) after kidney transplant. Total physical activity scores reflect household, work-related and leisure-time activities. Baseline demographics and physiologic parameters at admission were collected from medical records. Hypothesized predictors of physical activity were age, gender, race, comorbidities, prior transplant, previous dialysis, immunosuppressant drug type, BMI, systolic and diastolic blood pressure, creatinine, blood urea nitrogen, hemoglobin, hematocrit, and albumin levels. Variables significant on bivariate analysis were used in stepwise multiple regression to identify predictors of physical activity 6 months post kidney transplant.
Findings: The sample was 52.9% male with a mean age of 50.25±11.12 years. The most prevalent CAD risk was hypertension (86.8%); 26.5% were diabetics. The mean PASE score was 95.86±72.83 (range 0.25–307.75 out of a possible range of 0 –361) at 6 months, a score significantly lower than that reported in healthy subjects (131.3±70.4). On bivariate analysis, factors significantly associated with PASE score were age, gender, weight, creatinine, diastolic blood pressure and diabetes mellitus. In regression analysis, only gender (p<0.001) and age (p<0.004) were significant, explaining 25.3% of the variance in physical activity scores.
Conclusion: In the early months after transplant, kidney recipients engage in less physical activity than other groups and less activity than needed to decrease their CAD risk. Early efforts are particularly needed to help older patients and women to engage in physical activity to avoid development of CAD.