Abstract 1388: Illness Intrusiveness is an Independent Predictor of Self-Reported Physical Function in Patients With Coronary Artery Disease
Background. Perceptions of illness including illness-related threat and intrusiveness may affect physical function (PF). However, it remains unclear whether women with coronary artery disease (CAD) experience different illness perceptions than men and how illness perceptions overlap with depressive symptoms in explaining PF.
Objective. We examined relationships between gender, depressive symptoms (Beck Depression Inventory-II), CAD-related illness threat (Heart Disease Threat Scale) and intrusiveness (Adapted Illness Intrusive Rating Scale) and self-reported PF (Seattle Angina Questionnaire) in outpatients with CAD.
Method. Interviews were used to obtain demographic and clinical data on 90 community dwelling patients with self-reported CAD. Participants also completed a battery of study questionnaires. Independent samples t-tests were used to examine gender differences in illness perceptions and hierarchical multiple linear regression to determine how much of the unique variance in PF could be explained by heart disease threat (HT) and illness intrusiveness (IL) over and above what was explained by age, gender, years with CAD, and depressive symptoms (DEP).
Results. The sample was predominantly male (58.9%), married (60%), and Caucasian (80%) with a mean age of 67±11 years. On average, depressive symptoms were low (11.2±8.3). Women reported significantly (p < .05) greater HT, and greater IL in the 3 domains of physical well-being and diet, work and finances, and recreation and social relations. No gender differences were observed in DEP and the IL domains of marital, sexual, and family relations and other aspects of life. Regression model predictors accounted for 48% (p < .001) of the variance in PF. HD and IL accounted for 17.5% of unique variance in PF (p of R square change= .025). In the final model, older age (p=.012) and greater IL (p < .001) were predictors of poorer PF. DEP was not a significant predictor in the final model.
Conclusion. Controlling for depression, illness-related intrusiveness significantly predicted PF and was significantly higher in women across multiple domains. Interventions to enhance PF with CAD patients may need to address illness intrusiveness, especially for women.