Abstract 1362: Find the Glass Half Full? Optimism is Independently Protective of 10-year Incident CHD in a Population-based Study
Background: While some convenience studies have found that optimism is protective for risk of incident coronary heart disease (CHD), some have not. The objective of this study was to examine whether Optimism is protective in a population-based sample.
Methods: We conducted a prospective study of 2380 randomly selected Canadian men and women (50%) aged 18 to 92 years and free of CHD in 1995. The association between Optimism and 10-year incident CHD was estimated using Cox proportional hazards models adjusted for sex, age, all Framingham risk factors: systolic blood pressure, ratio of total cholesterol to high-density lipoprotein cholesterol, cigarette smoking in the past year, diabetes mellitus status at baseline.
Results: There were 274 incident CHD events (11.5%) during 19,730 person-years of follow-up. Optimism age-adjusted (hazard ratio, 0.88; 95% confidence interval, 0.79–0.99; P <.03) and multi-variable adjusted (hazard ratio 0.88; 95% confidence interval, 0.79–0.99; P=.02) predicted CHD incidence.
Conclusion: Increased optimism is associated with a reduced risk of 10-year incident CHD in this population-based sample, and provide preliminary findings to recommend targeted topics for CHD prevention in at-risk patients.