Abstract 1053: Systolic Blood Pressure Recovery From Exerce is Related to the Risk of Sudden Cardiac Death
Introduction: Limited information currently exists on the role of SBP during recovery period with the risk of sudden cardiac death (SCD).
Hypothesis: We assessed the association of systolic blood pressure (SBP) after exercise with the risk of an SCD in middle-aged men.
Methods: SBP was measured every two minutes during and after a progressive cycle ergometer exercise test in a representative population-based sample of 1808 Finnish men (age 42–61 years) without previous coronary heart disease. During an average follow-up period of 17 years, 75 SCDs occurred.
Results: An incremental rise of 10 mmHg per minute in SBP at 2 minutes after exercise (Hazard Ratio 1.11, 95 % confidence intervals 1.03 to 1.21, p= 0.031) was associated with the risk of SCD, after adjustment for age, alcohol consumption, smoking, serum lipids, diabetes mellitus, body mass index, regular use of antihypertensive medications, cardiorespiratory fitness, heart rate and ischemic ECG findings during exercise. Men with elevated systolic blood pressure of over 200 mmHg (highest quartile) after exercise had a 2.44-fold (95 % confidence intervals 1.07 to 5.58, p=0.034) risk for SCD as compared to those with SBP less than 166 mmHg (lowest quartile), after adjustment for age and other risk factors. Further adjustment for resting SBP and the use of antihypertensive medications weakened the observed associations.
Conclusions: SBP after exercise provides a predictive value for SCD. This emphasizes the importance of SBP measurements after the exercise test as it provides additional valuable prognostic measure with regard to SCD.