Abstract 707: The Diagnostic Accuracy of 256-Row Computed Tomographic Angiography Compared With Conventional Coronary Angiography in Patients With Suspected Coronary Artery Disease
Objectives: We sought to assess the diagnostic accuracy of 256-row computed tomographic angiography (CTA) in patients with suspected coronary artery disease.
Background: Noninvasive image of coronary artery by CTA is increasing used in recent years. The accuracy of 256-row CTA has not been studied yet. The aim of this study was to assess the accuracy of 256-row CTA compared with conventional coronary angiography (CCA) in the diagnosis and assessment of CAD.
Methods: We prospectively evaluated consecutive 63 individuals who accepted CTA and then underwent CCA. The presence of stenosis of 50% or more was considered obstructive. The diagnostic accuracy of CTA for detecting obstructive stenosis was compared with that of CCA. The area under the receiver-operating-characteristic curve (AUC) was used to evaluate the diagnostic accuracy of CTA relative to CCA.
Results: The segment-based analysis of CTA for detecting stenosis of 50% or more according to CCA revealed an AUC of 0.93 (95% confidence interval [CI], 0.87 to 0.99), with a sensitivity of 88.7%, a specificity of 93.1%, a positive predictive value of 73.2%, and a negative predictive value of 97.5%. The vessel-based analysis revealed an AUC of 0.93 (95% CI, 0.89 to 0.98), with a sensitivity of 94.4%, a specificity of 86.4%, a positive predictive value of 82.8%, and a negative predictive value of 95.7%.
Conclusions: 256-row CTA accurately identifies the presence and severity of CAD. Our data indicates that 256-row CTA has a powerful diagnostic ability and correlates well with CCA.