Abstract 258: A New Image Processing (4D Auto LVQ) for 3D Echocardiographic Left Ventricular Volumes Quantification
OBJECTIVE: To evaluate the accuracy and reproducibility of a new 3D real time echocardiographic semi automatic images processing (4D Auto LVQ, GE) for assessing left ventricular volumes and function.
METHODS: LV end-diastolic (LVEDV), end-systolic volumes (LVESV) and ejection fraction (LVEF) were computed using 4D Auto LVQ software in 54 patients (57±17 years, 64% men, 35% coronary artery disease) and compared to cine-MRI short axis measurements (Siemens 1.5T, Argus software). Intertechnique agreement was tested through linear regression and Bland-Altman analyses. Repeated measurements were performed to determine intraobserver and interobserver variability.
RESULTS: Time required for LV volumes analysis by 4D Auto LVQ averaged 147±12s. A close correlation was observed between MRI and 4D Auto LVQ for LVEDV (mean=162±64mL [80 –369], r2=0.89, p<0.001), LVESV (mean=92±61mL [28–299], r2=0.95, p<0.001) and LVEF (mean=47±16% [11–76], r2=0.8, p<0.001). In addition, Bland-Altman analysis (see figure⇓) showed a good agreement for LVEDV (SD=29mL), LVESV (SD=21mL) and LVEF (SD=7%) between 4D Auto LVQ and MRI with a slight underestimation of volumes by 4D Auto LVQ (mean bias −20ml and −18mL for LVEDV and LVESV respectively), which was not observed for EF (mean difference of 4%). Inter-observer variability for LV volumes and LVEF were 10% and 8% respectively.
CONCLUSION: 4D Auto LVQ available online provides an accurate and fast measurement of LV volumes and EF and may contribute to extend the clinical use of 3D echocardiography in daily practice.