Abstract P180: Cardiopulmonary Resuscitation With Military Anti-Shock Trousers in Emergency Department for Out-of-Hospital Cardiac Arrest: A 4-Month Randomized Pilot Study
Background: Recent experimental studies demonstrated that sustained abdominal compression during cardiopulomary resuscitation (CPR) significantly raised coronary perfusion pressure as a reliable predictor of success in CPR. If the more patients could be achieved the successful restoration of spontaneous circulation (ROSC), the more chances of the therapeutic hypothermia would be given to patients with out-of-hospital cardiac arrest (OHCA). The aim of this study was to evaluate that CPR with military anti-shock trousers (MAST) in emergency departments (EDs) for patients with OHCA could improve the short-term outcomes.
Methods: We conducted a pilot parallel-design randomized trial in three academic hospitals from June to October 2008. We randomly assigned adults who had had a non-traumatic OHCA to receive CPR with MAST (M-CPR) or conventional CPR (C-CPR) immediately after the arrival of ED. Each of CPR was performed based on the current CPR guidelines. The Primary end point was sustained ROSC, and the secondary end point was 24-hour survival.
Results: Among 64 patients, 33 were assigned to receive C-CPR and 31 to receive M-CPR. There were no significant differences in the baseline characteristics between the two groups. M-CPR was associated with significantly higher rates of sustained ROSC (61.3% vs. 30.3% in the C-CPR group; P=0.013). The rates of 24-hour survival in the M-CPR group was higher than that in the M-CPR group, however, it was not significantly different (29.0% vs. 12.1%; P=0.124).
Conclusion: Cardiopulmonary resuscitation with MAST in emergency departments for adults who had had an OHCA, was associated with significantly higher rates of sustained ROSC than the conventional CPR.