Abstract P157: Mechanical Cardiopulmonary Resuscitation (M-CPR) versus manual CPR according to pressure of end tidal Carbon Dioxide (PETCO2) during CPR in Out-of Hospital Cardiac Arrest (OHCA)
Background: Measuring pressure of end tidal Carbon dioxide (PETCO2) has in animal and human studies showed to be a practical non invasive method that correlates well with the pulmonary blood flow and cardiac output (CO), generated during cardiopulmonary resuscitation (CPR). This study was aimed to compare mechanical CPR (LUCAS, Jolife AB Sweden) vs. standard CPR according to PETCO2 among patients with out-of hospital cardiac arrest (OHCA), during CPR and with standardised ventilation.
Method: This prospective, on a cluster level, pseudo randomized trial took part in the Municipality of Göteborg. During a two year period all patients >18 years with out-of hospital cardiac arrest (OHCA) of presumed cardiac etiology were enrolled. Present analyse included only tracheal intubated patients where PETCO2 was measured in 15 minutes or until the detection of pulse giving rythm.
Results: In all, 126 patients participated in the evaluation, 64 patients in the mechanical chest compression group and 62 patients in the control group. The group receiving mechanical CPR resulted in the significantly highest values of PETCO2 according to the average (p=0.04), initial (p=0.01) and minimum (p=0.01) value. We found no significant difference according to the maximum value between groups.
Conclusion: Mechanical CPR during OHCA resulted in higher initial, minimum and average value of PETCO2. Since PETCO2 correlates well with pulmonary blood flow and CO generated during CPR these results recommends mechanical CPR to give the most effective chest compressions.