Abstract 5794: Clinical Risk Factors to Predict Deep Venous Thrombosis Post Endovenous Laser Ablation of Saphenous Veins
Introduction: Endovenous laser ablation of saphenous veins is an alternative to standard surgical vein stripping for the treatment of symptomatic varicose veins. Deep venous thrombosis (DVT) has been reported as a complication of such procedure with a rate of 1 to 5 %. Clinical risk factors to predict DVT post endovenous laser ablation are not well established.
Hypothesis: To establish clinical risk factors to predict DVT post endovenous laser ablation.
Method: Three hundred sixty consecutive patients who underwent endovenous laser ablation of saphenous veins were followed. Duplex ultrasound was performed within 1 week of the index procedure. DVT was defined as evidence of non-compressibility involving the sapheno-femoral, sapheno-popliteal junctions or any of the deep veins. Comparison between those with and without DVT was performed using step-wise logistic regression (SAS, SAS Institute, Cary, NC) to measure the correlation between continuous and categorical variables. The continuous variables included age, weight, glomerular filtration rate, distance of laser ablation, total energy used and the categorical variables included gender, diabetes mellitus, hypertension, hyperlipidemia, prior stroke, superficial venous thrombosis (SVT), DVT, coronary artery disease, peripheral arterial disease, and pulmonary embolism. Additional iterations were performed to determine the predictive power of various age thresholds. A p value < 0.05 was accepted as representing a significant difference.
Result: Nineteen DVTs were found on follow up ultrasound. Eighteen cases involved either the sapheno-femoral or sapheno-popliteal junctions. Only one case involved the deep venous system. Age > 66 (p = 0.007), female gender (p = 0.048) and prior history of SVT (p = 0.002) were associated with increased risk of DVT post endovenous laser ablation.
Conclusion: Age > 66, female gender and history of prior SVT are risk factors to predict DVT post endovenous laser ablation.