Influence of Prostigmine and Acetylcholine on Ventricular Fibrillation Elicited by Focal Cooling
Focal cooling of the exposed ventricle of the dog, beating at high rates, elicits ventricular fibrillation within a few seconds. The effect of this mode of cooling on hearts pre-treated with prostigmine or acetylcholine is studied. These compounds do not prevent ventricular fibrillation, but on the contrary some observations show that they enhance its appearance.
- © 1955 American Heart Association, Inc.