Abstract 5732: Regional and Global Myocardial Function in Patients with Hypertensive Heart Disease: A Two-dimensional Ultrasound Speckle Tracking Study
Aim of the study was to asses the effect of left ventricular hypertrophy (LVH) on regional and global myocardial function. Sixty-eight consecutive patients with arterial hypertension and normal coronary angiograms underwent conventional echocardiography. According to left ventricular mass index (LVMI) the patients were divided into three groups: none LVH, mild-moderate LVH (LVMI: 115–149 g/m2 for men and LVMI: 95–122 g/m2 for women) and severe LVH (LVMI > 149 g/m2 for men and LVMI: > 122 g/m2 for women). Two-dimensional greyscale loops were obtained from three apical (four-chamber, two-chamber and apical long axis) and three parasternal views (basal, mid, apical) of the LV at a frame rate of > 70 frames/s. Using a software for two-dimensional ultrasound speckle tracking, the absolute and the time to peak values of systolic strain (S) and strain rate (SRS) were extracted. For the calculation of LV twist, rotation curves were extracted from the basal and apical short axis view. After correcting for heart rate and spline interpolation, LV twist was calculated as difference between apical and basal LV rotation curves. Results are displayed in Table 1⇓. Patients with severe left ventricular hypertrophy had, according to the strain rate values, a reduced systolic function of the longitudinally and radial directed fibers. However, LVH seemed to have no impact on the degree of LV twist.