Abstract 4212: 64-MDCT Produces Significantly Lower Coronary Artery Calcium Scores than EBCT, with Coronary Motion Contributing to the Difference
Objective: To compare coronary artery calcium (CAC) scores on 64-slice multidetector CT (64-MDCT) and electron beam CT (EBCT) in study participants scanned on both scanners on the same day.
Methods: As part of the community-based Epidemiology of Coronary Artery Calcification Study, 170 participants underwent coronary artery calcium (CAC) scanning on 64-MDCT and EBCT on the same day. Differences in CAC Agatston scores were compared using a paired t-test. Two observers, blind to other analyses, reviewed 64-MDCT and EBCT images side-by-side by consensus. Images were anonymized for scanner type, and scored calcium in each image was highlighted. Observers identified artifacts that could account for differences between scans and identified which scan had fewer artifacts.
Findings: Agatston scores were significantly lower on 64-MDCT than on EBCT (216 ± 546 vs 269 ± 591, p = 0.0025). 95 of the 170 participants had at least one non-zero score and blind review of the images identified artifacts that could account for a difference in 48 cases (51% of non-zero). The most common artifact was coronary motion/blurring in the 64-MDCT reducing the detection of calcium (30 patients, 32% of non-zero). EBCT was determined to have fewer artifacts in 37 of the 48 (77%) participants with identified differences.
Conclusions: 64-MDCT produces lower CAC Agatston scores than EBCT and motion/blurring of vessels on 64-MDCT contributes to the difference. EBCT scans have fewer identifiable artifacts.