Abstract 4182: Tri-Dimensional Fusion Image Improves the Evaluation of Myocardial Perfusion
The purpose of this study was to obtain, in a non-invasive manner, a tri-dimensional (3D) fusion image of the myocardial perfusion, by integrating a single-photon emission computed tomography (SPECT) with a multidetector 64-slice-computed tomography coronary angiography (64-CTCA). A 3D fusion image was performed in 45 patients with myocardial perfusion defect. As a first step, the myocardial perfusion defect was detected through Thallium 201 SPECT stress-rest, via images made by Infinia Hawkeye 4g and computed by a Xeleris workstation (GE Healthcare Technologies, Milwakee,Wis). As a second step, a 64-CTCA (Light Speed VCT, GE) was performed on the same patients (Advantage Workstation, GE Healthcare Technologies). Finally, as a third step, 3D fusion images (Advantage Workstation, GE Healthcare Technologies) were obtained by integrating SPECT and 64-CTCA and the results of these images were compared to coronary angiographic segments (the gold-standard) which were undamaged, had a stenosis (> 50%), had calcified atherosclerotic plaque or had a stent. Out of a total of 540 coronary angiographic segments examined in 45 patients, 494 coronary angiographic segments were evaluated while 46 segments (9%) were excluded from further analysis caused by a lack of visibility and/or poor quality images. When using 3D SPECT/64-CTCA fusion images, an improvement of the sensibility, specificity, PPV and NPV were observed. We believe that this methodology offers an incremental diagnostic value and potentially could allow the carrying out of an earlier and more efficient treatment.