Abstract 2526: Comparison of 4 Years Efficacy and Durability of Drug-Eluting Stent Implantation in Non-Bifurcation and Bifurcation Lesion of Unprotected Left Main Coronary Arteries: Multicenter Registry in Asia
Aim: The aim of this study is to compare the 4 years safety and durability of drug-eluting stent implantation in non-bifurcation (ostium and/or mid shaft) (N-Bifur) and bifurcation (Bifur) lesion of unprotected left main coronary arteries (LMT).
Methods: A prospective analysis of 448 patients with LMT stenosis (324 Bifur and 124 N-Bifur) in five high volume Asian centers after successful stenting in LMT was performed. LMT was treated with 5 strategies (single stenting 195 cases, T-stenting 47 cases, crush stenting 38 cases, Mini-crush stenting 93 cases, culotte stenting 54 cases, kissing stenting 21 cases). Complete clinical follow-up to 4 years is being analyzed for all 448 patients.
Results: The baseline clinical characteristics between 2 groups were similar. Angiographic and clinical success were achieved in all patients without any major complication. At 4 years overall cardiac events of N-Bifur (14.5%) were significantly lower than Bifur (28.0%) (p=0.011). See figure for clinical results.
Conclusion: The use of drug-eluting stent in patients with LMT was safe and feasible with low acute complication and low incidence of restenosis. Drug-eluting stent implantation in non-bifurcation lesion of LMT showed lesser incidence of cardiac events (death, myocardial infarction, CABG and PCI) compared with those of bifurcation lesion at 4 years clinical follow-up.