Abstract 1062: Optimized Ventriculo-Arterial Interaction Explains Better Longitudinal Function in Endurance-Trained Athletes by Comparison with Strength-Trained Athletes
To assess differences in cardiac function induced by endurance- and strength- training.
To identify mechanisms of ventriculo-arterial interaction, and their effects on cardiac function.
69 male (21±4 years) were enrolled: 26 endurance-trained athletes (EA), 10 strength-trained athletes (SA), and a control group (C) of 33 age-matched sedentary subjects. Cardiac function was assessed by conventional and tissue Doppler echo: global systolic function from EF, short-axis function from PW, and long-axis systolic (STDE) and diastolic (ETDE) function from mean 6 basal segments velocities; arterial stiffness from augmentation index (AIx) and carotido-femural pulse wave velocity (PWV); endothelial function from flow mediated dilatation (FMD); and ventriculo-arterial interaction from amplitude of the compression wave (CW) from the wave intensity recordings. NT-proBNP, markers of myocardial fibrosis, and markers of oxidative stress (OS) were measured. Both groups of athletes had significant, but similar, LVH; EA had better longitudinal function (table⇓), whereas short-axis function was similar, associated with augmented arterial and endothelial function and lower OS, with improved ventriculo-arterial. NT-proBNP and markers of myocardial fibrosis were not different between the groups. Although both EA and SA have physiological LVH, endurance exercise is associated with better longitudinal function, due to optimized ventriculo-arterial interaction.