Abstract 699: Comparison of Diagnostic Criteria for Left Ventricular Non-compaction by Cardiac Magnetic Resonance
Introduction: Isolated left ventricular non-compaction (LVNC) does not have a universally accepted definition. Echocardiographic criteria may be equivocal and have not been applied to other imaging techniques. Our aim was to compare the diagnostic yield of different proposed criteria in a non-selected series of patients undergoing CMR
Methods: We reviewed 627 consecutive patients undergoing clinically indicated CMR in a 1.5 Tesla magnet. Steady state free precession cine images of the LV in the long (4-, 3-, and 2-chamber) and short-axis views were analyzed. The presence of LVNC was determined based on established CMR (A) nd echocardiographic (B, C) criteria, as shown in the Table⇓.
Results: There were 22 (3%) patients, (73% male, mean age 55 ± 11 years), who fulfilled diagnostic criteria for LVNC based on any criteria. Of these, 22 (100%) were diagnosed by criteria A, 19 (86%) by criteria B, and 10 (45.5%) by criteria C. Less than half, 10 (45%), fulfilled all 3 criteria. There was moderate agreement among the different methods (K coefficients A–B= 0.86, A–C= 0.58, B–C= 0.70).
Conclusions: Currently accepted CMR and echocardiographic criteria show significant variability for establishing the diagnosis of LVNC, with CMR criteria having the highest positive diagnostic rate. Consensus criteria applicable to multimodality imaging should be developed.