Abstract 6264: Factors for Inflammation of Carotid Plaque may be Different from Those for Carotid Plaque Formation
The underlying mechanism or factors for inflammation of plaques are unknown. 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) is capable of identifying and quantifying vascular inflammation within atherosclerotic plaques. We investigated factors for carotid artery inflammation evaluated by FDG-PET and compared them with factors for carotid atherosclerosis by carotid artery ultrasonography (CA-US). A total of 216 consecutive subjects (63±9 years) who received FDG-PET underwent CA-US. Carotid atherosclerosis was quantified by calculating the carotid intima-media thickness (IMT). Carotid artery inflammation was quantified by measuring the standardized uptake value (SUV) of FDG into the carotid artery. To determine the parameters of IMT and vascular inflammation, we performed multiple stepwise regression analysis. The Factors were different between IMT and vascular inflammation as shown in Table⇓. Our study suggests that metabolic factors may play a role in carotid vascular inflammation.