Abstract 1268: Beneficial Cardiovascular Effects of Bariatric Surgery Versus Dietary Weight Loss in Obesity
Bariatric surgery confers better long term weight management than dietary intervention, is a rapidly increasingly utilized method of weight management, and has been shown to reduce mortality. Despite this no study to date has addressed the relative beneficial effects of these different weight loss approaches on cardiac and aortic structure and function. In view of this, we used cardiovascular magnetic resonance imaging (CMR) to compare the effect of either Bariatric surgery or Dietary weight loss on left (LV) and right ventricular (RV) structure, LV diastolic function and regional aortic elastic function.
Method: 30 obese subjects, with no identifiable cardiovascular risk factors were recruited to the study. CMR was performed pre and post weight loss intervention, in 17 subjects on GI index diet (BMI 35.2 ± 5.5) and 13 subjects undergoing Bariatric surgery (BMI 45.6 ± 6.0kg/m2) for assessment of LV & RV mass (g), LV & RV end diastolic volume (EDV; ml), Diastolic Filling Rate (ml/s), and regional Aortic Distensibility (AD, mmHg−1 X 10−3) at 3 levels of the aorta (Ascending and Descending Aorta at the level of the pulmonary artery (PA) and the Abdominal Aorta)
Results: Both groups achieved significant weight loss, which tended to be greater after Bariatric surgery (p=0.32). Fasting serum glucose, cholesterol, systolic & diastolic blood remained within the normal range for both groups before and after intervention. Both groups had significant improvements in LV & RV mass, LV & RV EDV, diastolic filling rate and abdominal AD. When the improvements were normalized to percentage excess weight loss, there was no significant difference in the beneficial effects achieved in the surgical group to those seen in the dietary group for any of the cardiovascular parameters.
Conclusion: Irrespective of method, weight loss results in beneficial cardiovascular effects. Bariatric surgery and dietary weight loss provide similar levels of improvement in cardiovascular structure and function.