Abstract 6055: Vascular Complications Following Cardiac Catheterization and Interventions; Persistence of Gender Gap in the Contemporary Era
There are conflicting reports on gender difference in vascular complications following CATH and PCI. Earlier studies have shown that women experience more complications compared to men, while more recent reports have found no gender difference. The purpose of the study was to determine if vascular complications occur with greater frequency in women compared to men. A total of 1,519 (681female , 838 male) patients who underwent consecutive diagnostic CATH and PCI via femoral access at our institution between 2005 to 2007 were evaluated to determine if a gender gap exists in vascular complications. Chi-Square test or Fisher’s exact test were used to compare the incidence of complications among different risk factors. Odds ratios were calculated for various risk factors. Multivariate logistic regression was used to estimate the risk of getting complications. For the entire study population the incidence of any vascular complication was 3.02 %. For women it was 4.7 % and for men 1.67 % (p<0.0006). Comparing women to men the odds ratio (OR) for any vascular complications was 2.81 (95% CI: 1.51–5.22). Factors associated with increased vascular complications were renal failure (5.3 % vs. 2.5%, p< 0.05), HTN (3.6% vs. 1.26%, p=0.059), PCI (6.18% vs. 2.03% P< 0.0001), Vascular Closure Device (4.45% vs. 1.6%, p<0.004). African American race was associated with increased risk for retroperitoneal bleeding (p< 0.04). From multivariate logistic regression, female gender (OR=4.8), PCI (OR=2.9), and Vascular Closure Device (OR=5.1) were found to be significant independent predicators for having complications after controlling for other variables.
Conclusions: Following CATH and PCI
Women had more vascular complication than men.
Female gender was an independent predictor of vascular complications
Gender gap for vascular complications persists in the contemporary era.