Abstract 5797: Contribution of Basal, Middle and Apical Stroke Volume for Global Stroke Volume Assessed by Real-Time 3D Echocardiography
Background: Previous studies demonstrated that basal part of the myocardium has most contribution for global stroke volume (SV) using magnetic resonance imaging. Real-time 3D echocardiography (3DTTE) allows measuring regional and global SV without geometric assumption. The aim of this study was to examine the contribution of regional part of myocardium for global SV in normal volunteer, and to determine whether age and gender would affect the degree of regional contribution.
Methods: Full volume 3D datasets were acquired in 95 healthy volunteers with wide range of age (3– 88 years) by 3DTTE. Using quantitative software (QLAB, Philips), global and regional SV in 17-segment model were calculated. Regional SV from basal 6 segments, SV from middle 6 segments and SV from apical 5 segments were summed separately to generate basal, middle and apical SV in each subject. To adjust intersubject differences in heart rate and frame rate, interpolation was performed, and time sequence was normalized by 100-points. Global SV was corrected by body surface area (BSA). Subjects were divided into 4 groups according to age.
Results: No significant differences in BSA corrected global SV were noted among 4 groups (27±3, 29±9, 24±5, 23±5 ml/m2). The contribution of basal, middle and apical SV for global SV was roughly 40%, 40% and 20%, respectively. Age and gender did not alter percentage of regional contribution for SV.
Conclusions: In contrast to previous studies, basal and middle part of myocardium showed equal and dominant contribution for global SV. Apex was less important for global SV. These data could become a reference standard when determining regional contribution of SV in various disease status.